The design of a manufacturing systems is a complex and critical activity entailing decisions with an impact on a long time horizon and a major commitment of financial resources. Indeed, the modelling, simulation and evaluation of manufacturing systems are relevant activities both in the design and the operational phases of a factory. This paper grounds on the results of the Virtual Factory Framework (VFF) Project and addresses the use of an ontology based model of a production system to support the construction of a performance evaluation model. © 2014 The Authors. Published by Elsevier B.V.